Research Portfolio

Projects

Dr. Cash's projects span three connected themes: brain-body interactions in recovery, neuroplasticity and neuromodulation, and behavioral outcomes research.

Brain-body recovery

Brain-Body Interactions in Recovery

Projects in this area examine how brain health, autonomic function, obesity, and mobility interact during stroke recovery.

Obesity, brain health, and stroke recovery

NIH-funded work examining how obesity may limit brain health and influence recovery after stroke.

Resources
NIH LRP and D-SPAN award materials, study protocols, clinical and neurophysiological measures
Technology used
Clinical assessment, neurophysiological testing, statistical modeling, reproducible analysis workflows

Autonomia and chronic stroke

Research exploring associations between central autonomic network integrity and mobility performance after stroke.

Technology used
Neuroimaging-informed measures, mobility testing, statistical analysis, ECG, exploratory multimodal analysis

Neuromodulation

Neuroplasticity & Neuromodulation

Projects in this area use neuromodulation to understand lower-extremity sensorimotor plasticity and recovery.

Sensory motor integration & plasticity

Dissertation work characterizing lower-extremity neurophysiological responses to sensory augmentation in chronic stroke, alongside studies evaluating individualized paired associative stimulation as a tool to assay sensorimotor plasticity in healthy adults and people with chronic stroke.

Resources
Dissertation, NIH D-SPAN F99 materials
Technology used
Transcranial magnetic stimulation, sensory augmentation, paired associative stimulation

Lower-extremity neurophysiology

Work focused on lower-extremity motor threshold assessment, corticomotor excitability, and neuronavigated TMS methods that support individualized neuromodulation research after stroke.

Resources
NIH TL1/T32
Technology used
TMS, lower-extremity motor threshold assessment, neuronavigation

Outcomes research

Behavioral Outcomes Research

Projects in this area focus on measurement, function, and clinically meaningful outcomes in rehabilitation.

Functional Balance Ability Measure

Development and validation of a balance measure designed to capture ability across the spectrum of functional mobility after stroke and other neurologic diagnoses.

Resources
MUSC Emerging Scholars Travel Award
Technology used
Psychometric assessment, measurement validation, rehabilitation outcomes analysis

Gait analysis in severe post-stroke hemiparesis

Work comparing observational gait analysis with quantitative methods for individuals with severe post-stroke gait impairment.

Technology used
Gait event detection, observational analysis, quantitative movement assessment

Lower-extremity biomechanics and clinical outcomes

Research examining ankle angular velocity, acceleration, and other movement variables as reliable measures related to post-injury clinical outcomes.

Resources
Domer Research Award, Office of Student Research, Appalachian State University
Technology used
Biomechanics, kinematic analysis, kinetic analysis